“Caracterización clínica, terapéutica y pronóstica en nefritis lúpica, a propósito de un caso”

Abstract

Systemic lupus erythematosus is a chronic autoimmune disease characterized by the production of autoantibodies against a wide range of autoantigens. In most patients, numerous tissues and organs are involved, including the kidneys, heart, brain, joints and skin. One of the most severe complications of the disease is lupus nephritis, becoming an important cause of morbidity and mortality. Currently, the only Latin American prospective cohort (GLADEL) that included 1,214 patients with systemic lupus erythematosus, showed renal involvement in 51.7%. Although there is no epidemiological study in our country on Lupus Nephropathy is estimated according to research conducted at the Luis Vernaza Hospital that the number of Lupus erythematosus Sitemic reach 7,000 people, which corresponds to 0.1 to 0.3% of the population. The clinical case presented below concerns a 29-year-old female patient with a previous diagnosis of systemic lupus erythematosus, who presented renal manifestations in relation to nephrotic syndrome with high activity of her disease according to SLEDAI scale, received immunosuppressive dose with corticosteroid therapy, and a renal biopsy was scheduled to define the diagnosis, prognosis and treatment of lupus nephritis.