Volumen plaquetario medio y su estrecha relación con infecciones sépticas hospitalarias

Abstract

Objective: To determine the mean platelet volume (MPV) and its close relationship with hospital septic infections by means of a literature review. Materials and Methods: Information sources available in the Pubmed, Medicgraphic and SciELO databases were consulted, as well as the Google Scholar search engine. Publications in both English and Spanish were included, with a maximum of 5 years prior to the topic of interest. Results and Discussion: Original articles analyzing neonatal and adult populations with sepsis were analyzed. Neonatal populations reflected an elevated MPV value in the first 24 hours proving to be an early predictive marker in the diagnosis of neonatal sepsis, while studies of adult populationsreflected a much higher MPV in septic patients who subsequently died relative to those who survived, also being considered a predictor of mortality. Conclusion: It is evident that MPV is closely related to sepsis as it rises progressively during infection, constituting a biomarker of early prediction and poor prognosis in sepsis.