Efectos adversos del consumo de marihuana en el sistema cardiovascular

Abstract

Marijuana is the most widely used illicit drug worldwide, it contains more than 700 different chemical substances, in which phytocannabinoids are found, the best known being 9-tetrahydrocannabinol and cannabidiol. The 9-tetrahydrocannabinol ligandbinds to multiple receptors with especially high selectivity for cannabinoid receptor 1, which is predominantly expressed in the cardiovascular system, central nervous system, and peripheral vasculature in the brain. There is evidence to suggest that a higher frequency of marijuana use increases the risk of cardiac arrhythmias and myocardial infarction. The objective of this research was to relate chronic marijuana use to the development of adverse effects on the cardiovascular system. A search was carriedout in different databases such as Google Scholar, PubMed, Embase, Elseiver, Latindex, and Scielo, 35 abstracts of articles in both Spanish and English, published from 2018 to June 2022, were selected for review of the article s. which 11 were selected for the development of this review.