Browsing by Author "Alvarez Chasi, Katherine Janeth"

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    ALTERACIONES EN EL PERFIL LIPÍDICO Y TRANSAMINASAS SÉRICAS EN EL PRONÓSTICO DE ENFERMEDAD DE HÍGADO GRASO NO ALCOHÓLICO EN EL PERSONAL DEL GADM PÍLLARO
    (2025-02-25) Alvarez Chasi, Katherine Janeth; Galárraga Pérez, Edison Arturo; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    Non-alcoholic fatty liver disease (NAFLD) is a prevalent condition in individuals with overweight, obesity, and metabolic disorders, which can progress to advanced stages of liver damage, including steatohepatitis, fibrosis, and cirrhosis. This study aimed to analyze the relationship between lipid profile, serum transaminases, and factors such as age, sex, dietary habits, and body mass index (BMI) in the staff of GADM Píllaro. A cross-sectional observational study was conducted with 68 participants, collecting anthropometric (weight, height, BMI) and biochemical (total cholesterol, triglycerides, LDL, HDL, AST, and ALT) data. Statistical analyses included Chi-Square tests and Pearson and Spearman correlations, identifying significant associations between age and AST and ALT levels. The results revealed that 94.12% of the samples analyzed showed at least one alteration in the six biochemical parameters studied. Furthermore, 38.23% of the participants were at high risk of developing NAFLD, associated with multiple metabolic alterations and unfavorable conditions such as overweight, obesity, physical inactivity, and unhealthy dietary habits. In the lipid profile, the most frequently altered parameters were total cholesterol, HDL, and LDL. Additionally, an increase in serum transaminase levels was observed, suggesting possible hepatic impairment related to adverse metabolic and anthropometric factors.