Browsing by Author "Nieto Condo, Valeria Lilibeth"

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“Determinación del ancho de la curva de distribución Eritrocitaria en pacientes con dmt2 y su relación con el daño renal”
(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Laboratorio Clínico, 2017-02-01) Nieto Condo, Valeria Lilibeth; Cárdenas Ponce, Jorge Luis MD.
The present research project aimed to determine the Width of the Erythrocyte Distribution Curve (RDW) in patients with type 2 diabetes mellitus and its relation to renal damage. The RDW is an index to evaluate the variation of red blood cell volume. Recently, RDW was significantly associated with increased mortality in patients with Diabetes Mellitus, changes in RDW are also associated with the production of some inflammatory cytokines, and oxidative stress play an important role in the pathogenesis of damage renal. Regarding the methodology, the work approach was qualitative, applying field research, laboratory, and a level of longitudinal analytical research. We included 38 patients with DMT2 with a mean age of 60.39 ± 14.93 years of age. Each patient underwent two blood biometric and blood chemistry analyzes and correlated the values obtained. Based on the results of calculating the estimated glomerular filtration rate (eGFR) in the study population, it was possible to divide into 5 categories: 12 patients with normal or elevated glomerular filtration rate (GFR), 9 with Damage Renal and mild decrease in GFR, 1 with mild-moderate GFR, 2 with moderate GFR, and 14 with renal failure. Multiple logistic regression indicated that RDW (p <0.001) was an independent risk factor for kidney damage in mellitus diabetes type 2.
Diseño de implementación de un laboratorio de biología molecular en el Hospital Provincial General Docente Ambato
(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Centro de Posgrados, 2023-04-04) Nieto Condo, Valeria Lilibeth; Inca Torres, Alberto Renato
Molecular biology has improved the diagnosis and treatment of diseases at the genetic level, and the PCR technique is essential in the clinical laboratory. The implementation of a molecular biology laboratory in a hospital can be of great importance, and facilities, equipment, and personnel must be considered. In Ecuador, the General Teaching Hospital of Ambato needs a molecular diagnosis area to improve the quality of medical care and diagnostic support. The implementation of molecular biology laboratories in hospitals in Latin America has been a growing trend in the last decade, with successful examples in Argentina, Colombia, Mexico, Paraguay, Peru, and Brazil. These laboratories have been fundamental for the diagnosis of genetic and infectious diseases, allowing early detection and more precise treatment. The COVID-19 pandemic has highlighted the importance of laboratory diagnosis, and efforts have been made to standardize diagnostic procedures. The study was conducted at the General Teaching Provincial Hospital of Ambato in Ecuador, using an observational and descriptive research model with a qualitative approach. The study population included medical personnel, clinical laboratory technologists, and nurses working directly at the hospital. The sample size was 66 individuals. Data collection for the project involved a literature review and a survey to determine the need and feasibility of implementing a molecular biology laboratory in the hospital. The survey was conducted with 66 healthcare professionals and analyzed using statistical tools. There is a need and feasibility to implement a molecular biology laboratory in the General Teaching Hospital of Ambato in Ecuador, with the aim of improving the quality of medical care and diagnostic support.