Browsing by Author "Olmedo Muñoz, Melissa Belén"

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    EFECTO CARDIOMETABÓLICO DE LOS INHIBIDORES DEL COTRANSPORTADOR DE SODIO Y GLUCOSA TIPO 2
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2024-06-10) Olmedo Muñoz, Melissa Belén; Recalde Navarrete, Ricardo Javier
    Type 2 diabetes mellitus has emerged as a leading cause of premature death and a growing threat to the healthcare system due to the high costs of medical care in the context of cardiovascular complications. We conducted a systematic electronic search of clinical trials published from 2015 to January 2023 in PubMed, Scopus, Web of Science, and ScieLO databases, which evaluated the efficacy and safety of the use of sodium-glucose cotransporter type 2 inhibitors in patients with type 2 diabetes mellitus and established cardiovascular disease on standard therapy and their cost-effectiveness observing significantly lower rates of acute myocardial infarction, stroke, cardiovascular death and hospitalization due to heart failure when the study drugs were added to standard therapy. In addition, it was shown that the reduction in cardiovascular clinical events offset the cost of type 2 sodiumglucose cotransporter inhibitors, resulting in a cost-effective use of health care resources.