Browsing by Author "Sáez Paredes, Diana Nathaly"

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    ENFERMEDAD RENAL POLIQUISTICA AUTOSÓMICA DOMINANTE: ACTUALIZACIÓN DIAGNÓSTICO Y TRATAMIENTO
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2024-06-10) Sáez Paredes, Diana Nathaly; Lituma Jumbo, Rosalina de Lourdes
    Objective: This paper aims to consolidate and analyze the most recent data on the diagnosis and management of ADPKD, providing an updated synthesis to guide clinical practice and future research. Methodology: A thorough literature review was conducted, selecting studies, articles, and clinical guidelines published in the last decade. Inclusion criteria were based on clinical relevance, methodological quality, and the timeliness of the data. Non-peer-reviewed publications and those not contributing significant information to the central theme were excluded. Results: Advances in imaging have enhanced early detection and accurate assessment of the disease severity. Understanding the genetics and molecular biology of ADPKD has been crucial for the development of targeted therapies. Current treatments focus not only on delaying the progression of kidney disease but also on managing extrarenal manifestations and associated comorbidities. Conclusions: This pathology requires a multidisciplinary approach for its diagnosis and treatment. Advances in genomic and clinical research continue to improve the quality of life of affected patients. It is imperative for healthcare professionals to be up to date regarding recent developments to optimize clinical management and explore new avenues for research and therapeutic intervention.