Nutrición y Dietética

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    EFECTO DE LOS PROBIÓTICOS EN EL PACIENTE OBESO. UN ESTUDIO DE REVISIÓN
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Nutrición y Dietética, 2024-09-25) Montachana Crespata, Milena Alexandra; Viteri Robayo, Carmen Patricia
    Introduction: The gut microbiota is a potential determining factor in the development of obesity, resulting in dysbiosis, which is related to a lower number of members of the Bacteroidetes division and an increase in Firmicutes leading to a decrease in energy expenditure, it is also associated with the inflammatory process, insulin resistance and type 2 diabetes mellitus. Objective: To carry out a literature review related to the effects of probiotics on the improvement of the intestinal microbiota in an obese patient and its associated disorders. Methods: A search of articles in PubMed, Google Scholar and Elsevier from the last five years was carried out using the terms "obesity and probiotics", "effect of probiotics", "gut microbiota and probiotics". A total of 23 articles were included in the selection criteria. Results: Supplementation with probiotics specifically certain strains such as Lactobacillus plantarum and Bifidobacterium could lead to significant weight reductions, in combination with energy restriction and physical activity. However, it is important to develop clinical trials that are properly designed, including all aspects of lifestyle, gut microbiota, metabolites, and genetic background. Conclusions: Despite the beneficial effects, they are not yet considered an alternative strategy in the treatment of obesity due to the lack of research in this field, since the currently available data come from studies carried out in animals that may not present potential in humans. It is important to conduct more large-scale longitudinal studies with longer follow-up.
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    MICROBIOTA INTESTINAL EN LA OBESIDAD: REVISIÓN BIBLIOGRÁFICA
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Nutrición y Dietética, 2024-09-20) Gutierrez Lozada, Andres Eduardo; Guangasig Toapanta, Víctor Hernán
    Obesity and overweight is the abnormal and excessive accumulation of body fat. In recent decades they have become a global public health problem. The intestinal microbiota, which is the microbial ecosystem that colonizes the gastrointestinal tract, is involved in the pathogenesis of obesity. The objective of the present review is to compile the latest advances on the relationship between the intestinal microbiota in obesity and establish dysbiosis as an important factor in obesity, as well as the influence of diet on the intestinal microbiota and the consumption of prebiotics and probiotics. . . A methodology was used based on the bibliographic review of research related to the microbiota and obesity, carried out by exploring digital platforms specialized in health, such as Pubmed, Google Academic, ScIELO and Dialnet, in the period between 2019 and 2023. The results revealed that an imbalance in the intestinal microbiota is associated with an increased risk of obesity and related diseases. It is clear that the intestinal microbiota plays an important role in the pathogenesis of obesity.