Tesis Medicina Veterinaria y Zootecnia
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Item Evaluación de sevoflurano para mantenimiento anestésico por vía endotraqueal y transdémica a sacos aéreos caudales en pollos de engorde(2016) Cuesta Valle, Daniel Fernando; Villamarin Barragán, Darwin RafaelThe investigation entitled “Evaluation of Sevoflurane for Anesthetic Maintenance through Endotrachael and Transdermal Passages to Air Sack Flows in Broiler Chickens,” aimed to determine the minimal alveolar concentration (MAC) of sevoflurane suitable for producing immobility and hypnosis, the posed method utilizing twenty-four eight-week-old male broiler chickens. Those which were subjected to aerobic anesthetic for the evaluation were so done through different controlled doses or MAC (2.5%, 3.5%, 4.5% and 5.5%). It should be noted that pre-anesthetic drugs were not used owing to the desire to establish the suitable MAC of sevoflurane for maintenance. Sevoflurane anesthetic induction was performed using a mask for ten minutes, while anesthetic maintenance was performed through an endotracheal tube. At this stage, evaluations of heart rate (HR), respiratory rate (RR), pulse rate (PR), oxygen saturation (SpO2), and responses to superficial and deep nociceptive stimuli were carried out every five minutes for twenty-five minutes until it was determined that the endotraqueal passage with a MAC of 3.5% and 4.5% allowed for an anesthetic maintenance with resistance to superficial pain and immobility, while a MAC of 5.5% further deepens the anesthetic level with resistance to profound pain in 47% of cases, producing considerable depression of vital signs without however risk to the life of the bird, thus determining as a final result that sevoflurane is dose dependent, i.e. the higher the dose, the deeper the anesthetic level and depression of vital signs. While the transdermal application of sevoflurane to air sack flows produced neither immobility nor general anesthesia since the chickens recovered after two to three minutes after initiating the anesthetic maintenance.