Ciencias de la Salud

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Author: search.filters.author.Anchatipán Escobar, Juan CarlosSubject: search.filters.subject.ACETILCOLINESTERASA

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    “Pruebas bioquímicas y hematológicas en la valoración de intoxicación por organofosforados en agricultores del cantón Píllaro”
    (Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Laboratorio Clínico, 2018-04-01) Anchatipán Escobar, Juan Carlos; Vailati López, Juan Pablo Dr.
    Organophosphorus pesticides are chemical products that are used in an artisan way for plague control, in agricultural crops specially in potato crops, implying a high risk in people’s health who manipulate it directly, causing a decrease in the serum concentration of acetylcholinesterase and alterations in the liver function. The goal of this research is to determine the serum concentration of acetylcholinesterase in farmers exposed to Organophosphorus pesticides and to identify the possible variables that can alter the concentration of this enzyme; an experimental, predictive and bibliographic study was carried out, the study population were 40 farmers among men and women from canton of Píllaro, that were exposed directly with organophosphorus pesticides. For this study, the determination of serum the enzyme acetylcholinesterase, as well as liver enzymes, were performed by spectrophotometry techniques. It was determined that 7 out of 40 farmers exposed to organophosphorus pesticides showed a decrease in the concentration of the acetylcholinesterase enzyme representing 17.5% of the total study sample, a percentage that is not statistically significant according to the Student's t-test in relation to the total population, while in the determination of liver function enzymes no significant alterations were observed, it was also verified that the affected population had an exposure time between 11 and 31 years, as well as they were not aware of the biosecurity measures for the handling of this type of pesticides. Pesticides concluding that the decrease in acetylcholinesterase levels are directly influenced by the exposure time and the lack of knowledge of biosecurity measures in the handling of these pesticides.