Ciencias de la Salud

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IMPACTO DE LA MICROBIOTA INTESTINAL COMO DESENCADENANTE DE LA ENFERMEDAD DE PARKINSON
(2025-06-13) Morales Villacis Karen Alexandra; Padilla Vinueza Verónica Elizabeth; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Medicina
Years ago, it was believed that the gut microbiota only played a role in the digestion process. Today, it is known that it has a crucial impact on neurological health, to the extent that it has been associated with the development of Parkinson's disease. The objective of this research work is to analyze the role of the microbiota as a trigger for Parkinson's disease. This is a review of the literature related to gut microbiota and Parkinson's disease, which involved the collection and analysis of published bibliography over the last five years in both English and Spanish, yielding significantly relevant conclusions. Recent studies suggest that alterations in microbiota composition influence inflammation and metabolism, contributing factors to the progression of this disease. It is concluded that the bidirectional communication between the gut and the brain, known as the gut-brain axis, underscores the importance of microbiota in modulating the central nervous system, as it initiates systemic inflammatory processes that significantly influence the onset of Parkinson's disease.