Ciencias de la Salud
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Item CONSECUENCIAS DEL HIPOTIROIDISMO SUBCLÍNICO EN EL EMBARAZO(2025-06-13) Salazar Barroso, Kerly Noelha; Silva Acosta, Jissela del Carmen; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de MedicinaThe aim of the research was to understand the risks of subclinical hypothyroidism in pregnancy and the need for treatment for adequate foetal development. A review of scientific articles published from 2019 to 2024 in Google Scholar, Elsevier, Medigraphic and PubMed platforms was carried out, obtaining 4960 articles related to the topic, using inclusion criteria such as English and Spanish language articles published in the last 6 years of open access, excluding repeated research, documents not related to the subject and without relevance, 18 articles relevant to the research were selected. It was determined that during the gestation period in the mother there is an increase in thyroid hormone requirements, which in some cases causes dysfunction resulting in the development of subclinical hypothyroidism, which presents non-specific symptoms that require early screening and sometimes the use of drugs with levothyroxine when TSH values are greater than 4.0 mIU/L and sometimes requiring adjustments in the postpartum period. Based on the information obtained, it is concluded that subclinical hypothyroidism in pregnancy can cause serious complications such as pre-eclampsia, anaemia, placental abruption, and in the case of the foetus, low birth weight. Early detection and appropriate treatment are essential to reduce risks and optimise outcomes, thus improving the quality of life for the mother and foetus.Item RELACIÓN ENTRE LAS CONCENTRACIONES SÉRICAS DE HORMONAS TIROIDEAS Y EL PESO CORPORAL(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-13) Sani Nuñez, Viviana Lizeth; Ron Mora, Álvaro SebastiánThis study investigated the relationship between serum thyroid hormone concentrations and body weight. Thyroids as well hormone Thyroid stimulating hormone TSH, including thyroxine known as T4 and triiodothyronine known as T3, are essential for regulating energy metabolism and body weight. A detailed bibliographic search was used in scientific databases, selecting articles with greater relevance and methodological quality. Hypothyroidism, which is characterized by a lack of thyroid hormones, was associated with weight gain, while hyperthyroidism, which is characterized by an excess of thyroid hormones, was associated with weight loss. The findings support the existence of this complex connection and underscore the importance of considering both clinical experience and scientific evidence for an accurate diagnosis. In conclusion, alterations or modifications in thyroid function could have a significant impact on energy metabolism and weight management, as this field continues to evolve. These results could aid in the development of more effective public health plans to manage overweight and obesity.Item Terapias farmacológicas de reemplazo de la hormona tiroidea y su beneficio en la infertilidad femenina(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2022-11-01) Cóndor Martínez, Evelyn Dayana; Gavilanes Saenz, Víctor Patricio Md. Esp. Msc.The relationship between the endocrine function of the thyroid gland and the gametogenic function of the female gonads is well known. The prevalence of hypothyroidism in women between 20 and 45 years of age varies from 5 to 7% and the incidence is from 0.3% to 0.4%. Infertility is defined as the absence of pregnancy after at least 12 months have elapsed in women under 35 years of age or 6 months in those over 35 years of age who have had sexual intercourse without the use of any contraceptive method. The American Thyroid Association, the American Association of Clinical Endocrinologists and the American Endocrine Society recommend thyroxine (T4)-based treatment for women with thyroid hypofunction, and also establish that around 84.1% of infertile women who have thyroid disorders achieved a post-treatment clinical pregnancy. The objective is to review the most relevant bibliography about thyroid hormone replacement treatment and its benefit on female infertility to be applied in the local population; to which it is concluded that in all those infertile women, the evaluation of the serum thyroid profile should be carried out, which include T3, T4 and TSH, so that it can be diagnosed at an early stage of infertility to improve the rate of conception and avoid possible fetal complications during pregnancy. In addition, it is recommended to apply studies and insist on local research to corroborate that levothyroxine therapy shows benefits on female fertility in Ecuador.Item C a t e g o r i z a c i ó n d e l b i o t i p o y e s t a d o n u t r i c i o n a l e n p a c i e n t e s d i a g n o s t i c a d o s d e h i p o t i r o i d i s m o(Universdidad Técnica de Ambato/Facultad de Ciencias de la Salud/Centro de posgrados, 2021-09-01) Mesías Molina, Lucetty Yoled, Md.; Marizande Lozada, María Fernanda; Mg.Introduction: Knowing the biotype of a person is important, because it allows identifying specific characteristics of each human being, this contributes to planning their diet, lifestyle, and in case of having any disease, establish activities that reduce the morbidity of people. Objective: to identify investigations related to the categorization of the biotype and nutritional status in patients diagnosed with hypothyroidism supported by systematic reviews. Methodology: it was qualitative, descriptive under a systematic review research design, under certain inclusion criteria. Results: in the review developed, the main findings were that both men and women presented hypothyroidism, with a higher prevalence in women and in the age group of the adult population, since the average age was 40.7 years. Under the characteristics of weight, BMI and body fat, it was determined that the study group presented overweight and obesity and therefore, they are located in the endomorphic biotype. T3 values are directly related to weight, while it is indirectly related to cholesterol and triglycerides. Conclusions: The idea to be defended allows determining that the hypothyroidism and biotype of a person significantly affects their nutritional status, under these criteria, it is important to determine a self-care guide that contributes to patients with hypothyroidism to bring a better quality of life, depending on their food process and their specific biotype.