Ciencias de la Salud

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Start date: 2021Subject: search.filters.subject.INFLAMACIÓN

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    NUTRIGENÓMICA EN LA PREVENCIÓN DEL CÁNCER
    (2025-06-18) Romero Meza Jennifer Nathaly; Cruz Hidalgo Pablo Andrés; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Nutrición y Dietética
    Cancer is a disease that represents one of the leading causes of death worldwide and generates an extremely high economic impact on public health systems. However, a considerable number of cancer cases could be prevented through the adoption of appropriate dietary habits and the intake of foods rich in nutrients and bioactive substances. The aim of the present study is to synthesize and evaluate the effects and efficacy of certain bioactive compounds in the prevention of genetic alterations, improvement of the immune system or reduction of systemic inflammation that may lead to cancer. A systematic review was carried out following the PRISMA guidelines, in which studies from the last 5 years found in the Cochrane Library database were included. Considering the inclusion and exclusion criteria, a total of 16 randomized clinical trials were included. Which revealed and support that the incorporation of bioactive compounds present in food, such as polyphenols, carotenoids, glucosinolates, omega- 3 fatty acids, terpenes, phytosterols, lignans and antioxidants has a positive impact on cancer prevention by influencing various molecular mechanisms associated with it.
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    IMPACTO DE LA MICROBIOTA INTESTINAL COMO DESENCADENANTE DE LA ENFERMEDAD DE PARKINSON
    (2025-06-13) Morales Villacis Karen Alexandra; Padilla Vinueza Verónica Elizabeth; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de Medicina
    Years ago, it was believed that the gut microbiota only played a role in the digestion process. Today, it is known that it has a crucial impact on neurological health, to the extent that it has been associated with the development of Parkinson's disease. The objective of this research work is to analyze the role of the microbiota as a trigger for Parkinson's disease. This is a review of the literature related to gut microbiota and Parkinson's disease, which involved the collection and analysis of published bibliography over the last five years in both English and Spanish, yielding significantly relevant conclusions. Recent studies suggest that alterations in microbiota composition influence inflammation and metabolism, contributing factors to the progression of this disease. It is concluded that the bidirectional communication between the gut and the brain, known as the gut-brain axis, underscores the importance of microbiota in modulating the central nervous system, as it initiates systemic inflammatory processes that significantly influence the onset of Parkinson's disease.
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    Eficacia pronóstica de la relación plaquetas / linfocitos y la relación neutrófilos / linfocitos en pacientes con cáncer gástrico
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2023-03-01) López Altamirano, Joselyn Macarena; Rosero Freire, Daniela Alexandra Lic. Mg.
    Cancer is the main cause of death before age 70. Gastric cancer (GC) is responsible for 1 in 13 deaths worldwide and is predominant in men. Inflammation is closely related to cancer, as it activates differentblood cells such as neutrophils, lymphocytes, platelets, etc. A bibliographic review was carried out to collect and analyze studies concerning the prognostic efficacy of neutrophil/lymphocyte ratio (NLR) andplatelet/lymphocyte ratio (PLR) in patients with gastric cancer. Upon analysis, several studies indicatedthat elevated values of both NLR and PLR show poor prognosis. However, we suggest that more research is needed to obtain cutoff values according to GC staging, in order to bea helpful tool in GC diagnosis and prognosis
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    Proceso de atención de enfermería en pacientes con artritis juvenil
    (Universdidad Técnica de Ambato/Facultad de Ciencias de la Salud/Carrera de Enfermería, 2021-09-01) Toaquiza Espín, Andrea Mishell; López Pérez, Grace Pamela Lic. Mg.
    Juvenile Arthritis is a disease that affects during childhood, it is characterized by inflammation, destruction and wear of the joints, so being a great health problem because it can cause disability or even death. In this case, the nursing staff must be well connected with the patients due to the fundamental role of the nurse which is to reduce symptoms and improve the patient's lifestyle. Objective: To provide comprehensive nursing care to the patient with Juvenile Arthritis by applying the Nursing Care Process and using the NANDA Taxonomy. Method: A descriptive bibliographic review was carried out in the different scientific databases: Google Scholar, Scielo, Elsevier, PubMed, and through the DECS: Arthritis, inflammation, joints, polyarthritis. Results: Most of the reviewed articles agree that Juvenile Arthritis is a health problem that causes a clinical profile during childhood, because it generally causes joint deformity so reducing physical activity. It is essential to emphasize the importance of timely treatment in order to improve the patients’ lifestyle. Conclusions: The NANDA Taxonomy allows to health staff to identify interventions based on optimal care for the patient through symptomatology that allows to prioritize the care in an integral way and demonstrating the improvement of health and mood of the patients and the family.