Ciencias de la Salud
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Item CONSECUENCIAS DEL HIPOTIROIDISMO SUBCLÍNICO EN EL EMBARAZO(2025-06-13) Salazar Barroso, Kerly Noelha; Silva Acosta, Jissela del Carmen; Universidad Técnica de Ambato / Facultad de Ciencias de Salud / Carrera de MedicinaThe aim of the research was to understand the risks of subclinical hypothyroidism in pregnancy and the need for treatment for adequate foetal development. A review of scientific articles published from 2019 to 2024 in Google Scholar, Elsevier, Medigraphic and PubMed platforms was carried out, obtaining 4960 articles related to the topic, using inclusion criteria such as English and Spanish language articles published in the last 6 years of open access, excluding repeated research, documents not related to the subject and without relevance, 18 articles relevant to the research were selected. It was determined that during the gestation period in the mother there is an increase in thyroid hormone requirements, which in some cases causes dysfunction resulting in the development of subclinical hypothyroidism, which presents non-specific symptoms that require early screening and sometimes the use of drugs with levothyroxine when TSH values are greater than 4.0 mIU/L and sometimes requiring adjustments in the postpartum period. Based on the information obtained, it is concluded that subclinical hypothyroidism in pregnancy can cause serious complications such as pre-eclampsia, anaemia, placental abruption, and in the case of the foetus, low birth weight. Early detection and appropriate treatment are essential to reduce risks and optimise outcomes, thus improving the quality of life for the mother and foetus.Item RELACIÓN ENTRE LAS CONCENTRACIONES SÉRICAS DE HORMONAS TIROIDEAS Y EL PESO CORPORAL(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-13) Sani Nuñez, Viviana Lizeth; Ron Mora, Álvaro SebastiánThis study investigated the relationship between serum thyroid hormone concentrations and body weight. Thyroids as well hormone Thyroid stimulating hormone TSH, including thyroxine known as T4 and triiodothyronine known as T3, are essential for regulating energy metabolism and body weight. A detailed bibliographic search was used in scientific databases, selecting articles with greater relevance and methodological quality. Hypothyroidism, which is characterized by a lack of thyroid hormones, was associated with weight gain, while hyperthyroidism, which is characterized by an excess of thyroid hormones, was associated with weight loss. The findings support the existence of this complex connection and underscore the importance of considering both clinical experience and scientific evidence for an accurate diagnosis. In conclusion, alterations or modifications in thyroid function could have a significant impact on energy metabolism and weight management, as this field continues to evolve. These results could aid in the development of more effective public health plans to manage overweight and obesity.Item Terapias farmacológicas de reemplazo de la hormona tiroidea y su beneficio en la infertilidad femenina(Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Medicina, 2022-11-01) Cóndor Martínez, Evelyn Dayana; Gavilanes Saenz, Víctor Patricio Md. Esp. Msc.The relationship between the endocrine function of the thyroid gland and the gametogenic function of the female gonads is well known. The prevalence of hypothyroidism in women between 20 and 45 years of age varies from 5 to 7% and the incidence is from 0.3% to 0.4%. Infertility is defined as the absence of pregnancy after at least 12 months have elapsed in women under 35 years of age or 6 months in those over 35 years of age who have had sexual intercourse without the use of any contraceptive method. The American Thyroid Association, the American Association of Clinical Endocrinologists and the American Endocrine Society recommend thyroxine (T4)-based treatment for women with thyroid hypofunction, and also establish that around 84.1% of infertile women who have thyroid disorders achieved a post-treatment clinical pregnancy. The objective is to review the most relevant bibliography about thyroid hormone replacement treatment and its benefit on female infertility to be applied in the local population; to which it is concluded that in all those infertile women, the evaluation of the serum thyroid profile should be carried out, which include T3, T4 and TSH, so that it can be diagnosed at an early stage of infertility to improve the rate of conception and avoid possible fetal complications during pregnancy. In addition, it is recommended to apply studies and insist on local research to corroborate that levothyroxine therapy shows benefits on female fertility in Ecuador.Item C a t e g o r i z a c i ó n d e l b i o t i p o y e s t a d o n u t r i c i o n a l e n p a c i e n t e s d i a g n o s t i c a d o s d e h i p o t i r o i d i s m o(Universdidad Técnica de Ambato/Facultad de Ciencias de la Salud/Centro de posgrados, 2021-09-01) Mesías Molina, Lucetty Yoled, Md.; Marizande Lozada, María Fernanda; Mg.Introduction: Knowing the biotype of a person is important, because it allows identifying specific characteristics of each human being, this contributes to planning their diet, lifestyle, and in case of having any disease, establish activities that reduce the morbidity of people. Objective: to identify investigations related to the categorization of the biotype and nutritional status in patients diagnosed with hypothyroidism supported by systematic reviews. Methodology: it was qualitative, descriptive under a systematic review research design, under certain inclusion criteria. Results: in the review developed, the main findings were that both men and women presented hypothyroidism, with a higher prevalence in women and in the age group of the adult population, since the average age was 40.7 years. Under the characteristics of weight, BMI and body fat, it was determined that the study group presented overweight and obesity and therefore, they are located in the endomorphic biotype. T3 values are directly related to weight, while it is indirectly related to cholesterol and triglycerides. Conclusions: The idea to be defended allows determining that the hypothyroidism and biotype of a person significantly affects their nutritional status, under these criteria, it is important to determine a self-care guide that contributes to patients with hypothyroidism to bring a better quality of life, depending on their food process and their specific biotype.Item “Correlación entre la depresión y el hipotiroidismo”(Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Psicología Clínica, 2017-08-01) Guarnizo Gómez, María Salomé; García Ramos, Diana Carolina Ps. Cl. Mg.The present investigation is once to identify the correlation between the depression and hypothyroidism in out patients of the endocrinology service of the Ambato Provincial Teaching Hospital. Depression is mental disorder characterized by a low mood, followed by other symptoms such as feelings of guilt and disability, anhedonia, lack of sleep and appetite as well as fatigue and in severe cases recurrent thoughts of death orattempts may appear Suicidal; The evaluation of depression was done through the Beck Depression Test. Thyroid hormones are indispensable for metabolism in all body tissues, and where symptoms such as weight gain, dry skin, brittle hair, arthralgias and psychological symptoms such as fatigue, drowsiness, loss of intellectual quality can be found, for this variable was used Laboratory tests where the values of TSH and T4 were evidenced. The study sample consisted of 34 patients, and data analysis was performed in the SPSS statistical program through the square test (X2), thus proving that there is a dependence between the variables and therefore a relationship between Depression and hypothyroidism.Item Determinación de la Hormona Estimulante de la Tiroides (Tsh) y su relación con la Bilirrubina en Recién Nacidos con Ictericia(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Laboratorio Clínico, 2016-10-01) Moreno Moreno, Janeth Alexandra.; Tinajero Vásconez, María Fernanda B.Q.FJaundice is a yellowing of the skin and mucous membranes caused by the impregnation of bilirubin in the skin. Too much bilirubin is called hyperbilirubinemia in the newborn can cause brain damage called kernicterus. The thyroid is a gland located in the front of the neck, responsible for the secretion of thyroid hormones, thyroxine or T4, and triiodothyronine or T3. These hormones regulate important aspects of growth, development and functions of cells, organs and systems, metabolism of the heart, digestive tract and reproductive system, including neurons in the brain, these are affected when you do not have adequate levels. The main objective of the research is to determine the values of Thyroid Stimulating Hormone (TSH), free thyroxine values (FT4) and bilirubin in newborns with jaundice. An observational, descriptive, experimental and field research was conducted in the Department of Neonatology Provincial General Hospital in Latacunga October 2015 to March 2016. The enzymatic method was used for the determination of bilirubin and for determination of TSH and FT4 Immunoassay electrochemiluminescence "ECLIA" was used. The sample consisted of 50 newborns with jaundice who were in the area of neonatology Provincial General Hospital in Latacunga. Newborns may have jaundice when total bilirubin levels reach higher figures than 2.5 mg / dL and usually have two types of jaundice. Physiologic jaundice appears after 24 hours old, poses no harm to the newborn but is used as heliotherapy treatment is the use of sunlight. Pathological jaundice appears in the first 24 hours after birth, the newborn should receive immediate treatment to prevent severe damage. In the research we had 39 newborns who had physiological jaundice corresponding to 78% and 11 newborns had jaundice pathological corresponding to 22%. Infants who have low levels of Thyroid Stimulating Hormone (TSH) and high or normal levels of free thyroxine (FT4) tell us that the thyroid produces too much thyroid hormone and cause hyperthyroidism and newborns who have high levels TSH and low or normal FT4 values we indicate that the thyroid gland is not working properly and does not produce enough thyroid hormone and cause hypothyroidism. In research had 43 infants who had a normal diagnosis corresponding to 86%, 5 infants had a diagnosis of hypothyroidism is 10% and 2 newborns had a diagnosis of hyperthyroidism corresponding to 4%. Treatment for hypothyroidism should be administered levothyroxine and if you have hyperthyroidism is administered propranolol in the acute phase to reduce clinical symptoms or also radioactive iodine you get the same results but because of the risk of leukemia and cancer rarely used in pediatrics. In some cases surgical treatment is necessary.Item Calidad de vida de paciente con Hipertensión arterial más Hipotiroidismo enfocado a los cuidados de enfermería(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Enfermería, 2016-10-01) Soria Salinas, Alba Adriana; Herrera López, José Luis Lic. Mg.Hypertension obviously affect the quality of life of the sufferer to be this slow disease progression. Hypothyroidism triggers a hormonal imbalance that affects the patient who suffers, involving multiple health effects imbalanced. In this case an elderly patient, female, 69 years of age it suffering from Hypertension 8 years, Hypothyroidism 6 years ago, Diabetes Mellitushace 11 years, which is treated and control is presented, which affect to maintain a proper balance in their lifestyle, while causing further complications. During the investigation it became clear that the patient has emotional physical condition deteriorated by disease presented, in which different critical points identified risk factors that contributed to further complications that impair daily health by literature review appears different sources, interviews and analysis of clinical history, has managed to improve their lifestyle Mediate making a guide that presents the care they should take the patient based on the NIC and NOC activities. The guide designed for patients with hypertension and hypothyroidism in which prioritizes the needs presented, while helping to establish a balanced lifestyle to help improve the effects they present.Item Calidad de vida de paciente con Hipertensión Arterial más Hipotiroidismo enfocado a los cuidados de enfermería(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Enfermería, 2016-10-01) Soria Salinas, Alba Adriana; Herrera López, José Luis Lic. Mg.Hypertension obviously affect the quality of life of the sufferer to be this slow disease progression. Hypothyroidism triggers a hormonal imbalance that affects the patient who suffers, involving multiple health effects imbalanced. In this case an elderly patient, female, 69 years of age it suffering from Hypertension 8 years, Hypothyroidism 6 years ago, Diabetes Mellitushace 11 years, which is treated and control is presented, which affect to maintain a proper balance in their lifestyle, while causing further complications. During the investigation it became clear that the patient has emotional physical condition deteriorated by disease presented, in which different critical points identified risk factors that contributed to further complications that impair daily health by literature review appears different sources, interviews and analysis of clinical history, has managed to improve their lifestyle Mediate making a guide that presents the care they should take the patient based on the NIC and NOC activities. The guide designed for patients with hypertension and hypothyroidism in which prioritizes the needs presented, while helping to establish a balanced lifestyle to help improve the effects they present.Item Hipotiroidismo Congénito identificado por Tamizaje Neonatal en relación a los cuidados de enfermería(Universidad Técnica de Ambato-Facultad de Ciencias de la Salud-Carrera Enfermería, 2016-10-01) Ramírez Chicaiza, Fanny Verónica; Pulistar Manosalvas, Edison Norberto Dr.Congenital hypothyroidism (HTC) is usually diagnosed through neonatal screening that identifies the EIM (Inborn Errors) in the first hours or days after birth. It is to obtain blood by pricking the heel or umbilical cord and sent to the laboratory neonatal screening; the result can be obtained after 5 days. Congenital hypothyroidism is the most common endocrine disease of childhood, is the one that produces the most devastating effects on growth and development. It represents one of the few causes of mental retardation that can be preventable if diagnosed and treated early. Thyroid hormones are essential, among other functions, for the brain development of the child / girl wearing deficiency to mental retardation if not corrected early. The treatment consists of hormone replacement through ingestion of thyroid hormones; it should be initiated in the first weeks of life and maintained for life In this paper the case of a pediatric male patient, the same as suffering from congenital hypothyroidism occurs. Where the beginning, evolution of the disease, because the disease is working to care for the family from the knowledge of the disease to date, serving as a source for promoting the realization of a guide for parents care detailed patient with this disease. Risk factors are analyzed and considered whether these could be modified in some way to improve the quality of life of patients and their families.