Ciencias de la Salud

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    Alteraciones del perfil lipídico como factor de riesgo de insulinoresistencia en adolescentes con sobrepeso y obesidad
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2023-03-01) Pico Rivera, Patricia Nathaly; Pacha Jara, Ana Gabriela Bqf. Mg.
    Measurement of HOMA-IR is considered a vitally important test in the diagnosis and monitoring of insulin resistance. Previous studies have shown that alterations in weight, lipid profile and insulin can raise HOMA-IR concentrations independently of the patient's glycaemic status. Therefore, the aim of this study was to relate alterations in the lipid profile as a risk factor for the development of insulin resistance in overweight and obese adolescents aged 10 to 15 years, from the "La Providencia" Educational Unit, through the clinical determination of insulin, glucose, triglycerides, fasting cholesterol and HOMA-IR, obtaining as a result that 13 people with normal weight, of whom 11 women and 2 men presented altered concentrations of HOMAIR, Despite having a healthy glycaemia and lipid profile, in the pathological population (overweight and obesity), it was found that 27 people presented high concentrations of the HOMA index, divided into 17 women and 10 men, in which a slight alteration in their cholesterol, triglycerides or both was observed, so that in this study a relationship was found to exist between the alterations in the lipid profile values and the HOMAIR.
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    “Hipertensión arterial y su relación en las variaciones de la función renal residual en pacientes sometidos a diálisis en el centro de diálisis “contigo” de la ciudad de Latacunga en el periodo agosto 2011– febrero 2012”
    (Universidad Técnica de Ambato - Facultad de Ciencias de la Salud - Carrera de Medicina, 2012-05-01) Falcón Córdova, María José; Villacís Valencia, Sandra
    This study was a retrospective cross-sectional approach, spanned the period August 2011 to February 2012. The study population was 64 patients of both genders, with previous diagnosis of kidney disease stage V on dialysis process, attending the Renal Unit of the Clinic "You." A19 we excluded patients, 4 of whom died during the time studied, 3 had anury, 7 had constant post dialysis hypotension and 5 incomplete medical records. The results showed a higher incidence of women with 60%, the age of greatest risk comprises between 46-55 years with 26.7%, between 15 and 81 years of age half 42.2% is the antecedent hypertension followed by diabetes mellitus with a 22.2%, time of dialysis was> 7 months in 66.7%. Was identified that patients older than 66 years only 6.6%, the range of 46-55% decreased filtration majority 17.7%. In this relationship with the initial weight > 4 kg in a dry weight basis, 11.1% of them could control the T/A, but 4.4% was difficult to manage despite the ultrafiltration and antihypertensive medication, in patients 2-3 kg 26.6% controlled his T/A. The group of 0-1kg of water by weight 17.7% was difficult to control because it was renin-dependent hypertension. The decrease in glomerular filtration rate increased in patients with mixed hypertension (renin dependent volume) in 26.6% keeping the filtrate in a 4.4%, normotensive patients glomerular filtration rate increased by 6.6 % and decreased by 2.2% filtration. The renin affected more residual renal function decline in glomerular filtration rate by 20%. In patients who did not control blood pressure 35.5% decreased glomerular filtration rate confirming the hypothesis.