ABSCESO HEPÁTICO COMO PRECURSOR DEL CÁNCER COLORRECTAL

Abstract

Pyogenic cryptogenic liver abscesses (HA) have been called precursors of colorectal cancer (CRC). The importance of the relationship between these pathologies resides in the diagnosis and early treatment of cancer, so the investigation of the underlying causes of the development of cryptogenic liver abscesses is required. The objective of this review was to expose the studies that show the prevalence of AH as a preceding sign of CRC, from which a range of 1.9 to 13.9% was identified, according to studies of Asian populations. The location, number, and symptoms of AH did not show a specific relationship with the intestinal pathology, while diabetes mellitus and the presence of klebsiella pneumoniae were the incident factors in most CRC cases. One of the mechanisms identified was bacterial translocation from the altered intestinal wall, the pathogenesis of the microorganisms involved, and immunocompromised states. Together, these factors determine the development of liver abscesses as precursors of colonic neoplastic processes.