Eficacia de la polihexanida al 0,1% para el desbridamiento enzimático y eliminación de esfacelo en caninos (Canis lupus familiaris) con heridas por mordeduras

Abstract

The following work aimed to verify the effectiveness of polyhexanide for enzymatic debridement and removal of slough in canines with bite wounds. This research was carried out in the veterinary clinics (Candyvet and Dogtera) located in the province of Tungurahua in Ambato, where 22 patients with wounds due to a bite attended. The admitted patients were first subjected to a clinical examination where the size and depth of the wound were determined through exploration, followed by pre-washing to take a sample using a sterile swab for the counting of forming units. of colonies before the application of the treatment, after which an anesthetic protocol was applied to enter the operating room and, through ablation, make an opening that allows us to expose the lesion and evaluate its damage. Half of the patients who were admitted were then grouped to apply treatment with 0.1% polyhexanide in a sterile gauze, while the other half proceeded to apply 2% chlorhexidine directly to the affected area as a control treatment, leaving it act, after that the MAHVET wound instillation and coping technique was used, where a dressing was placed and the product was instilled according to its residual effect, after 3 days the dressing was changed and the sample was taken for shipment to the laboratory. Finally, the results were received from the laboratory to compare the pre-treatment and post-treatment CFU. Obtaining as a result a variety of colonies among which we can find: Enterobacter spp., Staphylococcus aureus, Proteus mirabillis, Enterococcus faecalis, Bacillus spp. Escherichia coli, coagulase negative Staphylococcus and beta hemolytic Streptococcus A. In addition, a significant difference was found in the percentage reduction of CFU between the group treated with 0.1% polyhexanide and 2% chlorhexidine, indicating a reduction of 97.44 % and 59.41% respectively. Thus, demonstrating the effectiveness of polyhexanide against chlorhexidine. Keywords: debridement, slough, polyhexanide, bacteria