Ciencias de la Salud

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Author: search.filters.author.Escudero Heredia Steeven PatricioSubject: search.filters.subject.FÁRMACOS

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    CARACTERIZACIÓN DE ESCHERICHIA COLI BLEE Y SALMONELLA SP. EN TRABAJADORES DE GRANJAS AVÍCOLAS DE LA ZONA 3
    (2025-02-24) Escudero Heredia Steeven Patricio; Jaramillo Ruales, Evelyn Katherine; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    The indiscriminate use of antibiotics in poultry farms promotes the emergence of resistant bacteria, such as ESBL-producing Escherichia coli and Salmonella sp., throughout the poultry production chain, posing a significant public health risk due to their potential for zoonotic transmission. This research project aimed to characterize ESBL-producing Escherichia coli and Salmonella sp. strains in poultry farm workers in Zone 3 from September 2024 to February 2025, through a descriptive crosssectional observational study. A total of 128 samples, including fecal and hand swabs from 64 workers, were analyzed. The results indicated an absence of Salmonella sp. colonization and a high prevalence of ESBL-producing E. coli (56%). The susceptibility profile showed low hydrolysis capacity for ceftazidime, moderate resistance to fluoroquinolones and aminoglycosides, and sensitivity to carbapenems. Furthermore, a predominance of the blaCTX-M gene (69%) was observed, along with a specific combination of blaCTX-M and blaTEM genes (25%), with no microorganisms carrying the blaSHV gene. Despite the high prevalence of colonization, it is not directly attributed to occupational practices in poultry farms, as it involves asymptomatic carriage of ESBL-producing E. coli. This phenomenon suggests shared reservoirs in which humans act as a link between bacteria and animals. Additionally, due to direct contact with poultry and the use of drugs throughout the food production chain intended for human consumption, there is a continuous dynamic of spreading multidrug-resistant bacteria.