Determinación del Perfil Hepàtico y su relación con la Hepatotoxicidad en Pacientes con Terapia Anticonvulsivante que asisten al Hospital General Docente Ambato

Abstract

The liver profile is a blood test that measures the presence of some proteins and enzymes such as bilirubin, and determine whether there is any alteration or diagnose liver disease, especially in people with certain disorders or treatment with potentially toxic drugs to the liver. This research project was made in order to determine the liver function and its relationship with hepatotoxicity in patients with anticonvulsant therapy attending the General Teaching Hospital Ambato, for this research involved 70 patients both men and women are treated in outpatient (epilepsy) in the H.P.D.A. these patients were took blood samples in order to determine whether or not hepatotoxicity, I underwent various liver tests and determined that if any changes thereof, the results of the various tests we got to alterations in liver profile and that these prevailing male with 39 patients, while females are 31 patients. The hypothesis testing was also performed by the statistical test with the coefficient of variation that allowed measuring the level of sensitivity of the tests. With the data obtained through the relationship between the test liver function and patient groups in a matrix worked crusade SSPS, the null hypothesis was rejected because there is sensitivity in tests of TGP and TP so that he accepted the alternative hypothesis.