Laboratorio Clínico

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    Vitamina B12 y trastornos hematológicos en la edad adulta tardía
    (Universidad Técnica de Ambato/Facultad de Ciencias de la Salud/Carrera de Laboratorio Clínico, 2023-03-22) Castillo Moposita, Katherine Paola; Ramos Ramírez, Martha Cecilia
    Objective: To analyze vitamin B12 and its relationship with hematological disorders in late adulthood, evaluating biomarkers of greater interest and reliability in the diagnosis of vitamin B12 deficiency. Methodology: An analytical, cross-sectional, field design was carried out that relates the causes to each other, obtaining the indicators of vitamin B12 and hematological disorders in the elderly. We included 85 patients from the Tisaleo canton of the province of Tungurahua characterized by being adults aged 65 to 90 years, both men and women, regardless of ethnicity, race, or social-economic situation Results: No association was found between low levels of vitamin B12 with anyhematological disorder, since the mean values of the sample are within normal parameters. However, decreased vitamin B12 concentrations were found at the 25th and 50th percentiles, but hemoglobin (HBG), hematocrit (HCT), and mean corpuscular volume (MCV) values were normal. At the 75th percentile, vitamin B12 levels were normal, but within the components of the blood count, mean corpuscular volume (MCV) was slightly elevated. Conclusions: Vitamin B12 is an essential substance that participates in different metabolic mechanisms of people. The study determined that levels of this vitamin are within normal parameters and was not associated with any hematological disorder.