Laboratorio Clínico

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Author: search.filters.author.Toalombo Caisa, Jennifer JohannaSubject: search.filters.subject.COLINESTERASA SÉRICA

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    DETERMINACIÓN DE COLINESTERASA SÉRICA EN AGRICULTORES EXPUESTOS A ORGANOFOSFORADOS DE LA PARROQUIA SANTA ROSA CANTÓN AMBATO
    (2025-02-25) Toalombo Caisa, Jennifer Johanna; Guangasig Toapanta, Víctor Hernán; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    The use of pesticides, essential for increasing agricultural productivity, has been crucial since the 20th century to ensure food security in the face of population growth. Among these, organophosphates stand out for their high toxicity and widespread use, particularly in developing countries. Exposure to organophosphate pesticides is a critical issue for the health of agricultural workers, as it is associated with the inhibition of serum cholinesterase. The aim of this research was to evaluate serum cholinesterase levels as an indicator of exposure to organophosphate pesticides in farmers from the Santa Rosa parish and to analyze the associated risk factors. The study employed a cross-sectional, observational, and analytical approach. The sample included 53 farmers selected based on inclusion criteria. A colorimetric method was used to measure serum cholinesterase, and structured surveys were employed to gather information on personal protective equipment (PPE) use and agricultural practices. The data were analyzed using statistical tests such as correlations and chi-square tests. The results showed that 9.4% of the farmers had a decrease in serum cholinesterase activity, associated with unsafe practices such as inadequate use of PPE (41.51%) and a high frequency of spraying (25.81%). It was concluded that prolonged exposure to organophosphates affects the health of farmers, emphasizing the need for regular monitoring of serum cholinesterase and training programs on safe agricultural practices. The proposal of this study is to implement surveillance systems and promote the proper use of PPE to reduce associated risks.