Laboratorio Clínico

Permanent URI for this collectionhttp://repositorio.uta.edu.ec/handle/123456789/817

Browse

Start date: 2022Subject: search.filters.subject.HELICOBACTER PYLORI

Search Results

Now showing 1 - 4 of 4
  • No Thumbnail Available
    Item
    TÉCNICAS MOLECULARES APLICADAS AL DIAGNÓSTICO DE HELICOBACTER PYLORI
    (2025-02-25) Martínez Tocagon, Katherin Mabel; Vilcacundo Córdova, Mario Fernando; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    Helicobacter pylori is a bacterium implicated in various gastrointestinal pathologies, including chronic gastritis, peptic ulcer and gastric cancer. Accurate and timely diagnosis of this infection is essential for its clinical management, especially in regions with high prevalence. For this reason, molecular techniques have emerged as essential tools to detect the presence of H. pylori in a more sensitive and specific manner, overcoming the limitations of traditional methods, such as bacterial culture and serological tests. The objectives of the present study were to describe and identify the molecular techniques applied for the diagnosis of Helicobacter pylori, to analyze their efficacy, and to determine their impact on the management of patients with this pathology. This review article describes the main molecular techniques used, such as polymerase chain reaction (PCR) and its variants, such as real-time PCR (qPCR), multiplex PCR, as well as other innovative techniques such as CRISPR-Cas13a-based PCR and next-generation sequencing (NGS), including their importance as well as their sensitivity and specificity from different studies.
  • No Thumbnail Available
    Item
    PREVALENCIA DE HELICOBACTER PYLORI DE LA POBLACIÓN ADULTA DE UNA ZONA RURAL DE TUNGURAHUA
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-13) Aucatoma Ayme, Blanca Yajaira; Yauli Flores, Carlos Fernando
  • No Thumbnail Available
    Item
    FACTORES DE RIESGOS ASOCIADOS A LA INFECCIÓN POR HELICOBACTER PYLORI EN ESTUDIANTES DE LA UNIDAD EDUCATIVA PEDRO CARBO DEL CANTÓN GUARANDA
    (Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico, 2024-08-05) Chacha Guaquipana, Erika Nayeli; Vilcacundo Córdova, Mario Fernando
    The bacterium Helicobacter pylori is a pathogen that colonizes more than half of the world's population, causing several gastrointestinal conditions. In Ecuador it has a high incidence of (70 and 80%), which is acquired at an early age due to exposure to various risk factors. The objective of this study was to establish the risk factors associated with Helicobacter pylori infection in students of the Pedro Carbo Educational Unit of the Guaranda canton, in order to determine its incidence and the risk factors that are directly related to the infection. A cross-sectional, observational and retrospective study was carried out, analyzing 133 stool samples for the detection of the Helicobacter pylori antigen by the immunochromatographic method, in addition, surveys were used for the collection of data/information and the SPSS Statistics Base program for the creation and analysis of graphs and tables. It was identified that the main risk factors associated with Helicobacter Pylori infection in the institution are: coexistence among several people (overcrowding), the non-availability of basic services, eating in the street, and the consumption of tap water at home.
  • No Thumbnail Available
    Item
    Helicobacter pylori en heces y su incidencia en patologías gástricas en pacientes de 30 a 70 años en el laboratorio clínico
    (Universidad Técnica de Ambato/Facultad de Ciencias de la Salud/Carrera de Laboratorio Clínico, 2022-09-01) Gavilanes Carrera, Sara Marlene; Galárraga Pérez, Edison Arturo, Dr. Mg.
    Gastrointestinal pathologies are one of the main causes of death worldwide, a variety of risk factors associated with this type of disease have been described, considering among the most important the socio-economic level, eating and hygienic habits, deficiency or absence of basic services, the bacterium that causes this infection is Helicobacter pylori, which affects the gastric mucosa, causing characteristic signs and symptoms, which affects people's health status. The objective of this research work was to determine the relationship between Helicobacter pylori and its incidence in gastric pathologies in patients aged 30 to 70 years in the Clinical Laboratory, the population that participated in the study was 60 people, between men and women, obtaining as a result 31 patients with positive Helicobacter pylori, of which 15 patients are female, which corresponds to 48.4%, while 16 patients are male, equivalent to 51.6%. The positive cases show that they have symptoms related to said infection, nausea, vomiting, recurrent diarrhea, abdominal pain and swelling before and after food intake. For this study, the determination of Helicobacter pylori in feces was carried out, through qualitative tests, it is important for an early diagnosis in people with symptoms associated with gastric pathologies and asymptomatic people, it is a bacterium studied in the last three decades, producing gastrointestinal problems. It is the most extensive chronic bacterial disease in the world, reflecting a higher prevalence in underdeveloped countries (80-90%), constituting a real public health problem, obtaining results that show high percentages of positive cases in people with associated symptoms. to infection, assuming as a final conclusion that people with an age range between 30 -40 years have prevalence in gastric pathologies.