Laboratorio Clínico

Permanent URI for this collectionhttp://repositorio.uta.edu.ec/handle/123456789/817

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    INCIDENCIA DE DERMATOFITOS EN PERSONAS DEDICADAS A LA AGRICULTURA EN EL SECTOR DE QUILLÁN LOMA
    (2025-02-25) Chimborazo Manobanda, Bryan Raúl; Vilcacundo Córdova, Mario Fernando; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    This study focuses on determining the frequency of dermatophytes in individuals engaged in agriculture in the Quillán Loma area. Dermatophytes, the most common agents of superficial mycoses worldwide, affect keratinized structures such as skin, nails, and hair. Farmers are particularly vulnerable due to their long working hours, contact with organic matter and animals, use of closed footwear, and humid conditions. The study, designed as cross-sectional, descriptive, observational, and prolective, included 52 participants with lesions suggestive of onychomycosis and athlete’s foot. Samples were collected from toenails, fingernails, sole scrapings, and interdigital spaces, and analyzed using 10% KOH, Sabouraud dextrose agar culture, microculture, and lactophenol blue staining. Microscopic and macroscopic analyses identified the etiological agents. Of the samples, 29 tested positives through KOH and culture. Nineteen dermatophytes were identified: Trichophyton mentagrophytes in 12 cases and T. rubrum in 7 cases. Additionally, 10 non-dermatophytic molds were isolated: Fusarium (5 cases), Aspergillus (3 cases), and one case each of Scopulariopsis and Alternaria. Risk factors were validated through a survey and correlated with the dermatophytes identified in the study.
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    DETERMINACIÓN DEL PERFIL HEPÁTICO Y COLINESTERASA SÉRICA EN AGRICULTORES EXPUESTOS A PESTICIDAS EN EL CASERÍO QUITOCUCHO DEL CANTÓN PELILEO
    (2025-02-25) Taipe Masaquiza, Carmen Marilyn; Ron Mora, Álvaro Sebastián; Universidad Técnica de Ambato/ Facultad de Ciencias de Salud /Carrera de Laboratorio Clínico
    The present study aimed to evaluate the levels of liver enzymes and serum cholinesterase in farmers exposed to pesticides in the Quitocucho hamlet of the Pelileo Canton. Pesticides are essential for pest control in different agricultural crops, but their cumulative toxicity can generate negative effects on the health of farmers, including liver damage, neurological disorders and respiratory problems. A cross-sectional, descriptive, observational and prolective study was used, where 90 blood samples were analyzed from women and men. The quantification of liver enzymes was performed on the Auto-Chemistry Analyzer CS-T180 and serum cholinesterase on the Erba Mannhein spectrophotometer. Through an evaluated survey, the risk factors associated with the inadequate handling of pesticides were identified through nonparametric tests, such as Mann-Whitney, Kruskal-Wallis and Chi square. The results indicated slightly elevated levels of AST in 34.4% (31 farmers), ALT in 24.4% (22 farmers), GGT in 20% (18 farmers), ALP in 16.7% (15 farmers) and decreased serum cholinesterase in 8.9% (8 farmers). To establish whether there is a relationship between liver enzyme alterations and exposure to pesticides, the Chi-square test was used. The results showed that there is no significant relationship, which suggests that the alterations in liver enzymes could be associated with other factors.